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Shown
are two pictures are of the HyHel-5 (anti-lysozyme) Fv. This image is
looking down the beta-barrel, with the CDRs toward the viewer. It shows
the various loops that make up the CDR region: L1=red, L2=yellow,
L3=blue, H1=red, H2=yellow, H3=green.
Here
is the same view but with "spherical harmonic surface envelopes"
plotted as a mesh. It demonstrates the "hand-shake" of the interlocking
saddles at the VH/VL domain interface. For more information on
spherical harmonics as it relates to molecular modeling see Dave Ritchie's webpage
This final image illustrates the HyHel-5/lysozyme complex, shown as a pair of low-resolution spherical harmonic surfaces.
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