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HyHel-5 (anti-lysozyme) Fv

Shown are two pictures are of the HyHel-5 (anti-lysozyme) Fv. This image is looking down the beta-barrel, with the CDRs toward the viewer. It shows the various loops that make up the CDR region: L1=red, L2=yellow, L3=blue, H1=red, H2=yellow, H3=green.

HyHel-5 (anti-lysozyme) Fv - spherical harmonic surface envelopes

Here is the same view but with "spherical harmonic surface envelopes" plotted as a mesh. It demonstrates the "hand-shake" of the interlocking saddles at the VH/VL domain interface. For more information on spherical harmonics as it relates to molecular modeling see Dave Ritchie's webpage

HyHel-5/lysozyme complex | spherical harmonic surfaces

This final image illustrates the HyHel-5/lysozyme complex, shown as a pair of low-resolution spherical harmonic surfaces.